Last update
3/10/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.3
USERS' SCORE
Good
Based on 11 Reviews
8.9
Supplement Facts
Serving Size: 1 Level Teaspoon (approx. 2 g)
Serving Per Container: About 85
Amount Per Serving
%DV
Calories
10
Total Carbohydrate
2 g
<1%*
Total Sugars
2 g
†
Organic D-Mannose
2 g (2,000 mg)
†
Top Medical Research Studies
8
We explored how D-mannose could help prevent urinary tract infections and discomfort in patients undergoing cystoscopy. In a well-structured study with 32 patients, those receiving D-mannose experienced significantly fewer UTIs and less severe urinary symptoms compared to those who did not receive treatment.
While the treatment showed promise by reducing the number of infections and pain, no major difference was found in overall quality of life scores between the groups. This indicates D-mannose could be beneficial for specific discomforts related to the procedure.
While the treatment showed promise by reducing the number of infections and pain, no major difference was found in overall quality of life scores between the groups. This indicates D-mannose could be beneficial for specific discomforts related to the procedure.
Read More
7
Yeast impacts sperm quality negatively
We examined how certain yeast strains affect male fertility, particularly by observing their influence on sperm quality.
Our research revealed that these yeast strains altered conventional sperm parameters like viability and motility when incubated together.
Interestingly, while functional parameters showed changes, these were not statistically significant. However, pretreating sperm with mannose did reduce the impact of the yeast, suggesting that the yeast's interaction with sperm is likely mediated through mannose receptors.
Our research revealed that these yeast strains altered conventional sperm parameters like viability and motility when incubated together.
Interestingly, while functional parameters showed changes, these were not statistically significant. However, pretreating sperm with mannose did reduce the impact of the yeast, suggesting that the yeast's interaction with sperm is likely mediated through mannose receptors.
Read More
4
D-mannose has limited preventive effects
We considered how D-mannose and other lifestyle changes might help prevent recurrent urinary tract infections. Our review looked into various preventative measures, including hygiene and diet.
We found that D-mannose can potentially help by preventing harmful bacteria from sticking to the urinary tract. However, its effectiveness may vary based on the dosage. While these methods are generally well-tolerated, they are not guaranteed solutions.
We concluded that a mix of dietary adjustments and proper hydration could serve as an alternative to long-term antibiotic treatment.
We found that D-mannose can potentially help by preventing harmful bacteria from sticking to the urinary tract. However, its effectiveness may vary based on the dosage. While these methods are generally well-tolerated, they are not guaranteed solutions.
We concluded that a mix of dietary adjustments and proper hydration could serve as an alternative to long-term antibiotic treatment.
Read More
Most Useful Reviews
10
Quick symptom relief
29 people found this helpful
This product really works!! After a year of struggling with Candida, I found D-Mannose a blessing during my menstrual cycle when symptoms flared. Initially, I experienced a headache, which indicated toxins being released. However, after adjusting the dosage and drinking plenty of water, my symptoms vanished within two days. D-Mannose has been incredibly effective at combating the yeast infection while supporting my overall health. I wholeheartedly recommend this product!
Read More
9
Quick yeast infection help
13 people found this helpful
Must have. For over a year, I battled symptoms of BV and vulvodynia, compounded by countless antibiotics worsening my condition. D-Mannose drastically improved my symptoms and even helped clear my yeast infections when taken with water consistently over a week. It is nearly tasteless, and I encourage anyone with recurring issues to give it a try. D-Mannose is a game changer for those suffering from cystitis and persistent infections.
Read More
10
Life-changing relief
8 people found this helpful
CURED MY LIFETIME CHRONIC UTI'S! Since childhood, I've battled UTIs monthly, often accompanied by yeast infections from antibiotics. After eight years of using D-Mannose, I found it effectively resolved my UTIs within a day. My urologist, impressed with my results, now recommends it to other patients. This simple sugar loosens the grip of E. coli, allowing it to be flushed away rather than increasing antibiotic resistance. D-Mannose has truly transformed my life for the better.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.3
- All Researches
8
We explored how D-mannose could help prevent urinary tract infections and discomfort in patients undergoing cystoscopy. In a well-structured study with 32 patients, those receiving D-mannose experienced significantly fewer UTIs and less severe urinary symptoms compared to those who did not receive treatment.
While the treatment showed promise by reducing the number of infections and pain, no major difference was found in overall quality of life scores between the groups. This indicates D-mannose could be beneficial for specific discomforts related to the procedure.
While the treatment showed promise by reducing the number of infections and pain, no major difference was found in overall quality of life scores between the groups. This indicates D-mannose could be beneficial for specific discomforts related to the procedure.
Read More
7
Yeast impacts sperm quality negatively
We examined how certain yeast strains affect male fertility, particularly by observing their influence on sperm quality.
Our research revealed that these yeast strains altered conventional sperm parameters like viability and motility when incubated together.
Interestingly, while functional parameters showed changes, these were not statistically significant. However, pretreating sperm with mannose did reduce the impact of the yeast, suggesting that the yeast's interaction with sperm is likely mediated through mannose receptors.
Our research revealed that these yeast strains altered conventional sperm parameters like viability and motility when incubated together.
Interestingly, while functional parameters showed changes, these were not statistically significant. However, pretreating sperm with mannose did reduce the impact of the yeast, suggesting that the yeast's interaction with sperm is likely mediated through mannose receptors.
Read More
4
D-mannose has limited preventive effects
We considered how D-mannose and other lifestyle changes might help prevent recurrent urinary tract infections. Our review looked into various preventative measures, including hygiene and diet.
We found that D-mannose can potentially help by preventing harmful bacteria from sticking to the urinary tract. However, its effectiveness may vary based on the dosage. While these methods are generally well-tolerated, they are not guaranteed solutions.
We concluded that a mix of dietary adjustments and proper hydration could serve as an alternative to long-term antibiotic treatment.
We found that D-mannose can potentially help by preventing harmful bacteria from sticking to the urinary tract. However, its effectiveness may vary based on the dosage. While these methods are generally well-tolerated, they are not guaranteed solutions.
We concluded that a mix of dietary adjustments and proper hydration could serve as an alternative to long-term antibiotic treatment.
Read More
User Reviews
USERS' SCORE
Good
Based on 11 Reviews
8.9
- All Reviews
- Positive Reviews
- Negative Reviews
10
Quick symptom relief
29 people found this helpful
This product really works!! After a year of struggling with Candida, I found D-Mannose a blessing during my menstrual cycle when symptoms flared. Initially, I experienced a headache, which indicated toxins being released. However, after adjusting the dosage and drinking plenty of water, my symptoms vanished within two days. D-Mannose has been incredibly effective at combating the yeast infection while supporting my overall health. I wholeheartedly recommend this product!
Read More
9
Quick yeast infection help
13 people found this helpful
Must have. For over a year, I battled symptoms of BV and vulvodynia, compounded by countless antibiotics worsening my condition. D-Mannose drastically improved my symptoms and even helped clear my yeast infections when taken with water consistently over a week. It is nearly tasteless, and I encourage anyone with recurring issues to give it a try. D-Mannose is a game changer for those suffering from cystitis and persistent infections.
Read More
10
Life-changing relief
8 people found this helpful
CURED MY LIFETIME CHRONIC UTI'S! Since childhood, I've battled UTIs monthly, often accompanied by yeast infections from antibiotics. After eight years of using D-Mannose, I found it effectively resolved my UTIs within a day. My urologist, impressed with my results, now recommends it to other patients. This simple sugar loosens the grip of E. coli, allowing it to be flushed away rather than increasing antibiotic resistance. D-Mannose has truly transformed my life for the better.
Read More
9
Improves UTI frequency
5 people found this helpful
Kick those UTIs!! I am thrilled with D-MANNOS! I’ve struggled with recurrent UTIs but found that taking D-Mannose twice or thrice a day helps manage symptoms effectively. I drink a teaspoon mixed with water and follow it with hydration to flush out bacteria. While I still have UTIs occasionally, they are infrequent compared to before. D-Mannose has become my go-to remedy, and I should never run out of it!
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10
Stands out among treatments
4 people found this helpful
This product is a life saver. After enduring monthly UTIs and the ensuing yeast infections from antibiotics, I tried D-Mannose and haven’t had a UTI since starting five months ago. It’s easy to take, with a slight sweetness, and I take it daily. Stopping even for a few days resulted in returning symptoms, but it works effectively when used consistently. The cost pales in comparison to my previous expenses for treatment.
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Frequently Asked Questions
References
- Quattrone C, Manfredi C, Napolitano L, Ferraro A, Distefano C, et al. D-Mannose Plus to Prevent Urinary Tract Infections and Discomfort after Cystoscopy: A Single-Center Prospective Randomized Pilot Study. Medicina (Kaunas). 2023;59. 10.3390/medicina59061165
- Castrillón-Duque EX, Puerta Suárez J, Cardona Maya WD. Yeast and Fertility: Effects of Activity of spp. on Sperm Quality. J Reprod Infertil. 2018;19:49. PubMed
- Armelle J. [Recurrent cystisis: No medicine preventive means]. Prog Urol. 2017;27:823. 10.1016/j.purol.2017.09.006
Data last updated:
