Research Authors

Overview

SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.3
USERS' SCORE
Good
Based on 88 Reviews
8.9
Supplement Facts
Serving Size: 1 Level Teaspoon (approx. 2 g)
Serving Per Container:  About 85
Amount Per Serving
%DV
Calories
10
 
Total Carbohydrate
2 g
<1%*
Total Sugars 
2 g
†
Organic D-Mannose
2 g (2,000 mg)
†

Top Medical Research Studies

We explored how D-mannose could help prevent urinary tract infections and discomfort in patients undergoing cystoscopy. In a well-structured study with 32 patients, those receiving D-mannose experienced significantly fewer UTIs and less severe urinary symptoms compared to those who did not receive treatment.

While the treatment showed promise by reducing the number of infections and pain, no major difference was found in overall quality of life scores between the groups. This indicates D-mannose could be beneficial for specific discomforts related to the procedure.
7
Yeast impacts sperm quality negatively
We examined how certain yeast strains affect male fertility, particularly by observing their influence on sperm quality.

Our research revealed that these yeast strains altered conventional sperm parameters like viability and motility when incubated together.

Interestingly, while functional parameters showed changes, these were not statistically significant. However, pretreating sperm with mannose did reduce the impact of the yeast, suggesting that the yeast's interaction with sperm is likely mediated through mannose receptors.
4
D-mannose has limited preventive effects
We considered how D-mannose and other lifestyle changes might help prevent recurrent urinary tract infections. Our review looked into various preventative measures, including hygiene and diet.

We found that D-mannose can potentially help by preventing harmful bacteria from sticking to the urinary tract. However, its effectiveness may vary based on the dosage. While these methods are generally well-tolerated, they are not guaranteed solutions.

We concluded that a mix of dietary adjustments and proper hydration could serve as an alternative to long-term antibiotic treatment.

Most Useful Reviews

9
Infection-free living
53 people found this helpful
An AMAZING product! I endured chronic bladder infections for almost five years, trying numerous antibiotics and alternative treatments. Then, someone recommended D-Mannose, and I thought "why not?" I bought it, and within hours, my symptoms vanished. I'm now free from infections, antibiotics, and yeast infection. D-Mannose is fantastic; I wish I'd known about it five years ago.
10
No more infections
39 people found this helpful
Excellent! No more UTIs thanks to D-Mannose. Unlike many products filled with additives, this is purely D-Mannose, and it's organic. It dissolves quickly in water and tastes great. After using it for a year while managing an indwelling catheter, I haven't had a single infection. I simply mix one teaspoon in water daily. It's 100% effective—no more antibiotics for me!
10
Quick symptom relief
29 people found this helpful
This product really works!! After a year of struggling with Candida, I found D-Mannose a blessing during my menstrual cycle when symptoms flared. Initially, I experienced a headache, which indicated toxins being released. However, after adjusting the dosage and drinking plenty of water, my symptoms vanished within two days. D-Mannose has been incredibly effective at combating the yeast infection while supporting my overall health. I wholeheartedly recommend this product!

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.3
  • All Researches
We explored how D-mannose could help prevent urinary tract infections and discomfort in patients undergoing cystoscopy. In a well-structured study with 32 patients, those receiving D-mannose experienced significantly fewer UTIs and less severe urinary symptoms compared to those who did not receive treatment.

While the treatment showed promise by reducing the number of infections and pain, no major difference was found in overall quality of life scores between the groups. This indicates D-mannose could be beneficial for specific discomforts related to the procedure.
7
Yeast impacts sperm quality negatively
We examined how certain yeast strains affect male fertility, particularly by observing their influence on sperm quality.

Our research revealed that these yeast strains altered conventional sperm parameters like viability and motility when incubated together.

Interestingly, while functional parameters showed changes, these were not statistically significant. However, pretreating sperm with mannose did reduce the impact of the yeast, suggesting that the yeast's interaction with sperm is likely mediated through mannose receptors.
4
D-mannose has limited preventive effects
We considered how D-mannose and other lifestyle changes might help prevent recurrent urinary tract infections. Our review looked into various preventative measures, including hygiene and diet.

We found that D-mannose can potentially help by preventing harmful bacteria from sticking to the urinary tract. However, its effectiveness may vary based on the dosage. While these methods are generally well-tolerated, they are not guaranteed solutions.

We concluded that a mix of dietary adjustments and proper hydration could serve as an alternative to long-term antibiotic treatment.

User Reviews

USERS' SCORE
Good
Based on 88 Reviews
8.9
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Infection-free living
53 people found this helpful
An AMAZING product! I endured chronic bladder infections for almost five years, trying numerous antibiotics and alternative treatments. Then, someone recommended D-Mannose, and I thought "why not?" I bought it, and within hours, my symptoms vanished. I'm now free from infections, antibiotics, and yeast infection. D-Mannose is fantastic; I wish I'd known about it five years ago.
10
No more infections
39 people found this helpful
Excellent! No more UTIs thanks to D-Mannose. Unlike many products filled with additives, this is purely D-Mannose, and it's organic. It dissolves quickly in water and tastes great. After using it for a year while managing an indwelling catheter, I haven't had a single infection. I simply mix one teaspoon in water daily. It's 100% effective—no more antibiotics for me!
10
Quick symptom relief
29 people found this helpful
This product really works!! After a year of struggling with Candida, I found D-Mannose a blessing during my menstrual cycle when symptoms flared. Initially, I experienced a headache, which indicated toxins being released. However, after adjusting the dosage and drinking plenty of water, my symptoms vanished within two days. D-Mannose has been incredibly effective at combating the yeast infection while supporting my overall health. I wholeheartedly recommend this product!
9
Quick yeast infection help
13 people found this helpful
Must have. For over a year, I battled symptoms of BV and vulvodynia, compounded by countless antibiotics worsening my condition. D-Mannose drastically improved my symptoms and even helped clear my yeast infections when taken with water consistently over a week. It is nearly tasteless, and I encourage anyone with recurring issues to give it a try. D-Mannose is a game changer for those suffering from cystitis and persistent infections.
10
Antibiotic-free option
12 people found this helpful
D-Mannose spared my four-year-old daughter from long-term antibiotic use for chronic bladder infections. We’d visited the emergency room frequently, but opting for D-Mannose instead of antibiotics proved beneficial. It detaches e-coli from the bladder wall, allowing her to flush out the pathogens. A daily teaspoon kept her infection-free for extended periods, and she hasn’t needed antibiotics for over a year!

Frequently Asked Questions

10
Antibiotic-free treatment
5 people found this helpful
This product works! I had no complaints — everything is as promised and even better. After taking 9 grams per day, I found relief after half a day, and after two days, the infection disappeared without antibiotics. I plan to continue using it but at a reduced dose and will order more!
9
Saved from antibiotics
10 people found this helpful
This product has been a game-changer for my uncle! He is quadriplegic and had been on antibiotics for years due to UTIs, depleting his good bacteria and making him increasingly ill. After starting D-Mannose, he was a changed person within a week. We just ordered two more bottles to ensure we never run out. He has not had a single infection since and is now antibiotic-free since January. He is so much more comfortable and happier, with noticeable weight gain. Our whole family is ecstatic! Highly recommend!
9
No more symptoms
6 people found this helpful
As a long-term sufferer of yeast infections, I have tried nearly everything available, including two surgeries. Upon reading about D-Mannose powder and with my doctor's advice, I started it a year ago, and I have not experienced any symptoms of those painful infections since. Thank you, iHerb, for the great savings on your Now Foods D-Mannose powder!
9
Infection-free living
53 people found this helpful
An AMAZING product! I endured chronic bladder infections for almost five years, trying numerous antibiotics and alternative treatments. Then, someone recommended D-Mannose, and I thought "why not?" I bought it, and within hours, my symptoms vanished. I'm now free from infections, antibiotics, and yeast infection. D-Mannose is fantastic; I wish I'd known about it five years ago.
10
No more infections
39 people found this helpful
Excellent! No more UTIs thanks to D-Mannose. Unlike many products filled with additives, this is purely D-Mannose, and it's organic. It dissolves quickly in water and tastes great. After using it for a year while managing an indwelling catheter, I haven't had a single infection. I simply mix one teaspoon in water daily. It's 100% effective—no more antibiotics for me!
10
Antibiotic-free option
12 people found this helpful
D-Mannose spared my four-year-old daughter from long-term antibiotic use for chronic bladder infections. We’d visited the emergency room frequently, but opting for D-Mannose instead of antibiotics proved beneficial. It detaches e-coli from the bladder wall, allowing her to flush out the pathogens. A daily teaspoon kept her infection-free for extended periods, and she hasn’t needed antibiotics for over a year!
9
Lasting results
3 people found this helpful
I had frequent visits to the doctor for chronic yeast infections and even a kidney infection from one. After trying various antibiotics without success, I tried D-Mannose daily for two months and now only take it if I suspect a yeast infection is starting. I haven't had one in over a year! This product is simply the best. Thank you so much! Highly recommend!
9
Long-term freedom
8 people found this helpful
After enduring chronic yeast infections, I began taking one teaspoon of D-Mannose powder daily. I managed to go an entire year without any infections until I forgot it on a trip and developed a yeast infection swiftly afterwards.

References

  1. Quattrone C, Manfredi C, Napolitano L, Ferraro A, Distefano C, et al. D-Mannose Plus to Prevent Urinary Tract Infections and Discomfort after Cystoscopy: A Single-Center Prospective Randomized Pilot Study. Medicina (Kaunas). 2023;59. 10.3390/medicina59061165
  2. Castrillón-Duque EX, Puerta Suárez J, Cardona Maya WD. Yeast and Fertility: Effects of Activity of spp. on Sperm Quality. J Reprod Infertil. 2018;19:49.
  3. Armelle J. [Recurrent cystisis: No medicine preventive means]. Prog Urol. 2017;27:823. 10.1016/j.purol.2017.09.006
image